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New PhD topics of our department: here

 All publications of our authors (since 2015): here

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k Phonebook of the Department    
     

Professors:

   
     

Prof. Radek Cibulka

e +420 22044 4182

d A 278c

b Radek.Cibulka@vscht.cz 

Head of Department www ResearcherID
     

Prof. Pavel Lhoták

e +420 22044 5055

d A 249

b Pavel.Lhotak@vscht.cz

  www  
     

Prof. Jaroslav Kvíčala

e +420 22044 4240

d A 278d

b Jaroslav.Kvicala@vscht.cz

  www  
     

Prof. Jiří Svoboda

e +420 22044 3688

d A 278e

b Jiri.Svoboda@vscht.cz

  www  
     

Associate Professors:

   
     

Assoc. Prof. Jan Budka

e +420 22044 4284

d A 251

b Jan.Budka@vscht.cz

DOC web editor www  
     

Assoc. Prof. Jana Hodačová

e +420 22044 4173

d A 270

b Jana.Hodacova@vscht.cz

  www  
     

Assoc. Prof. Michal Kohout

e +420 22044 5012

d A 258

b Michal.Kohout@vscht.cz

  www  
     

Assoc. Prof. Igor Linhart

e +420 22044 4165

d A 266

b Igor.Linhart@vscht.cz

  www  
     

Assoc. Prof. Tomáš Tobrman

e +420 22044 4245

d A 271

b Tomas.Tobrman@vscht.cz

 RIT www  
     

Assistant Professors:

   

Dr. Michal Himl

e +420 22044 4165

d A 266

b Michal.Himl@vscht.cz

  www  
     

Dr. Roman Holakovský

e +420 22044 4279

d A 255

b Roman.Holakovsky@vscht.cz

  www  
     

Dr. Petr Kovaříček

e +420 22044 2040

d B3 207

b Petr.Kovaricek@vscht.cz

www

Dr. Václav Kozmík

e +420 22044 4118

d A 308

b Vaclav.Kozmik@vscht.cz

  www  
     

Dr. Martin Krupička

e +420 220 444 173
d A 268
b Martin.Krupicka@vscht.cz

  www  
     

Dr. Ondřej Kundrát

e +420 22044 4280

d A 253

b Ondrej.Kundrat@vscht.cz

www ResearcherID 
     

Dr. Petra Ménová

e +420 22044 3686

d A 268

b Petra.Menova@vscht.cz

  www  

Dr. Pavla Perlíková

e +420 22044 2039

d B3 206

b Pavla.Perlikova@vscht.cz

www
     

Dr. Markéta Rybáčková

e +420 22044 4242

d A 259

b Marketa.Rybackova@vscht.cz

Secretary of Department

www  
     

Dr. Eva Svobodová

e +420 22044 4249

d A 260

b Eva.Svobodova@vscht.cz

  www  
     

Technicians:

   

Květa Bártová

e +420 22044 3686

d A 268

b Kveta.Bartova@vscht.cz

   
     

Ivana Bocková, MSc.

e +420 22044 4280

d A 250

b Ivana.Bockova@vscht.cz

   
     
Michaela Kadlecová 

e +420 22044 4276

d A 262

b Michaela.Kadlecova@vscht.cz
   
     

Martina Kovandová

e +420 22044 4279

d A 255

b Martina.Kovandova@vscht.cz

   
     

Vladimír Kuneš

e +420 22044 4277

d A L06

b Vladimir.Kunes@vscht.cz

   
     

Jana Netušilová

e +420 22044 4164

d A 278a

b Jana.Netusilova@vscht.cz

Administrative Support of Department  
     

Markéta Slabochová, MSc.

e +420 22044 4059 

d A 308  

b Marketa.Slabochova@vscht.cz

Economist of Department  
     

Helena Štenglová 

e +420 22044 4278 

d A 257 

b Helena.Stenglova@vscht.cz

   
     

Ing. David Tetour

e +420 22044 4173

d A270

b David.Tetour@vscht.cz

Marta Tokárová 

e +420 220 444 245 

d A 271 

b Marta.Tokarova@vscht.cz

   
     

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Essential Information for Current Students



Bachelor Students

Master Students

PhD Students

Lectures delivered by members of the Department

  • Toxicology and ecology
  • Organic chemistry I, II and III
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  • Organic chemistry of selected elements

Repository of the theses

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DATA


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In the last years, we have been focusing on inherently chiral derivatives which can be obtained via relatively simple reactions in the meta-position of a (thia)caliarene skeleton (see publications); some examples of last results:
 

Intramolecularly Bridged Calix[4]arenes with Pronounced Complexation Ability toward Neutral Compounds

Slavik, P.; Eigner, V.; Lhotak, P.
Org. Lett. 2015, 17, 2788-2791
 DOI:10.1021/acs.orglett.5b01200 


Abstract Image 

Abstract: Regioselective derivatization via an organomercury intermediate allowed for the introduction of carboxylic acid functionality into the meta position of the calix[4]arene skeleton. Intramolecular Friedel–Crafts cyclization led to a novel type of calixarene containing a ketone bridging moiety. Subsequent attack of the ketone by organometallic compounds occurred selectively from outside providing tertiary alcohols with the OH group oriented inside the cavity. These compounds can complex neutral molecules both in the solid state (X-ray) and in solution (NMR) using the cooperative effect of hydrogen bonding (OH) and CH−π interactions from within the cavity.

 

Shaping of Calix[4]arenes via Double Bridging of the Upper Rim

Slavik, P.; Eigner, V.; Lhotak, P.
Cryst. Eng. Comm. 2016, 18, 4964-4970
DOI:10.1039/C6CE00314A

 

Graphical abstract: Shaping of calix[4]arenes via double bridging of the upper rim 

 

Abstract: Direct double meta-mercuration can be used for subsequent bridging of a calix[4]arene skeleton via the installation of ketone moieties. This unprecedented substitution pattern in calixarene chemistry possesses a heavily distorted and rigid cavity capable of interactions with selected molecular guests as documented by binding of a CH2Cl2 molecule held in place by an intricate net of 10 specific (halogen bonding and hydrogen bonding) interactions from two neighbouring calixarene molecules

 


Calix[4]arene Containing a Ureido Functionality on the Lower Rim as Highly Efficient Receptors for Anion Recognition

Klejch, T.; Slavicek, J.; Hudecek, O.; Eigner, V.; Gutierrez, N. A.; Curinova, P.; Lhotak, P.

New J. Chem. 2016, 40, 7935-7942
 DOI:10.1039/c6nj01271j


Graphical abstract: Calix[4]arenes containing a ureido functionality on the lower rim as highly efficient receptors for anion recognition

 

Abstract: The introduction of nosyl moieties onto the lower rim of the calix[4]arene skeleton led to the formation of compounds immobilised in cone conformations. Subsequent reduction of the nitro group and reaction with aryl isocyanates enabled the construction of new calixarene-based ligands for anion recognition. As proven by NMR and UV/vis titration experiments, diaryl urea moieties with electron-withdrawing substituents on both sides represent very efficient tools for the complexation of selected anions (AcO, BzO, H2PO4) even in highly competitive solvents such as DMSO-d6.

 

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