Patent

Gaálová, F. Yalcinkaya, P. Cuřínová, M. Kohout, I. Stibor, P. Izák: Kompozitní chirální membrána, způsob její přípravy a způsob obohacování směsí enantiomerů, číslo patentu: 308513, datum udělení: 2.9.2020.

Publikace 2021

1. Skopalová H., Kozmík V., Šmahel M., Svoboda J., Pacherová O., Kohout M. Mesomorphic properties of non-symmetric bent-core liquid crystals with a lateral substituent in the apex position. Liq. Cryst. 2021, accepted.
   https://doi.org/10.1080/02678292.2020.1836567
   
   
2. Cigl M., Hampl F., Svoboda J., Podoliak N., Stulov S., Kohout M., Novotná V. Laterally substituted biphenyl benzoates – synthesis and mesomorphic properties. Liq. Cryst. 2021, accepted.
   https://doi.org/10.1080/02678292.2020.1794069
   
   
3. Spálovská D., Paškan M., Jurásek B., Kuchař M., Kohout M., Setnička V. Structural spectroscopic study of enantiomerically pure synthetic cathinones and their major metabolites, New J. Chem. 2021, 45, 850.
   https://doi.org/10.1039/D0NJ05065B
   
   
4. Wolrab D., Frühauf P., Kolderová N., Kohout M. Strong cation- and zwitterion-exchange-type mixed-mode stationary phases for separation of pharmaceuticals and biogenic amines in different chromatographic modes. J. Chromatogr. A 2021, 1635, 461751. 
   https://doi.org/10.1016/j.chroma.2020.461751

Publikace 2020

1. Poryvai A., Bubnov A., Kohout M. Chiral Photoresponsive Liquid Crystalline Materials Derived from Cyanoazobenzene Central Core: Effect of UV Light Illumination on Mesomorphic Behavior. Crystals 2020, 10, 1161.
   https://doi.org/10.3390/cryst10121161
   
   
2. Tlustý M., Spálovská D., Kohout M., Eigner V., Lhoták P. Ketone transformation as a pathway to inherently chiral rigidified calix[4]arenes. Chem. Commun. 2020, 56, 12773.
   https://doi.org/10.1039/D0CC05352J
   
   
3. Skopalová H., Špaček P., Kozmík V., Svoboda J., Novotná V., Pociecha D., Kohout M. The Role of Substitution in the Apex Position of the Bent-Core on Mesomorphic Properties of New Series of Liquid Crystalline Materials. Crystals, 2020, 10, 735.
   https://doi.org/10.3390/cryst10090735
   
   
4. Guselnikova O., Postnikov P., Kolská Z., Záruba K., Kohout M., Elashnikov R., Švorčík V., Lyutakov O. Homochiral metal-organic frameworks functionalized SERS substrate for atto-molar enantio-selective detection. Appl. Mater. Today 2020, 20, 100666.
   https://doi.org/10.1016/j.apmt.2020.100666
   
   
5. Kolderová N., Jurásek B., Kuchař M., Lindner W., Kohout M. Gradient supercritical fluid chromatography coupled to mass spectrometry with a gradient flow of make-up solvent for enantioseparation of cathinones. J. Chromatogr. A 2020, 1625, 461286.
   https://doi.org/10.1016/j.chroma.2020.461286
   
   
6. Tlustý M., Dvořáková H., Čejka J., Kohout M., Lhoták P. Regioselective Formation of Quinazoline Moiety on the Upper Rim of Calix[4]arene as the Way to Inherently Chiral Systems. New J. Chem. 2020, 44, 6490.
   https://doi.org/10.1039/D0NJ01035A
   
   
7. Šmahel M., Poryvai A., Xiang Y., Pociecha D., Troha T., Novotná V., Svoboda J., Kohout M. Photosensitive bent-core nematic liquid crystals with various linking units in the side arms: Structure-properties relationships. J. Mol. Liq. 2020, 306, 112743.
   https://doi.org/10.1016/j.molliq.2020.112743
   
   
8. Cigl M., Jurok R., Hampl F., Svoboda J., Podoliak N., Novotná V.: Lateral substituted phenyl biphenylcarboxylates ‒ non-chiral analogues of ferroelectric liquid crystals. Liq.  Cryst. 2020, 47, 768-776.
   https://doi.org/10.1080/02678292.2019.1679903
   
   
9. Gaálová J., Yalcinkaya F., Cuřínová P., Kohout M., Yalcinkaya B., Koštejn M., Jirsák J., Stibor I., Bara J. E., Van der Bruggen B., Izák P. Separation of racemic compound by nanofibrous composite membranes with chiral selector. J. Membr. Sci. 2020, 596, 117728.
   https://doi.org/10.1016/j.memsci.2019.117728
   
   
10. Otmar M., Gaálová J., Žitka J., Brožová L., Cuřínová P., Kohout M., Hovorka Š., Bara J. E., Van der Bruggen B., Jirsák J., Izák P. Preparation of PSEBS membranes bearing (S)-(-)-methylbenzylamine as chiral selector. Eur. Polym. J. 2020, 122, 109381.
    https://doi.org/10.1016/j.eurpolymj.2019.109381

Publikace 2019

9. Jing, H.; Xu, M.; Xiang, Y.; Wang, E.; Liu, D.; Poryvai, A.; Kohout, M.; Éber, N.; Buka, A.: Light tunable gratings based on flexoelectric effect in photoresponsive bent-core nematics. Adv. Opt. Mater. 2019, 1801790.
   https://doi.org/10.1002/adom.201801790
   
   
10. Pokluda, A.; Kohout, M.; Chudoba, J.; Krupička, M.; Cibulka, R.: Nitrosobenzene: Reagent for the Mitsunobu esterification reaction. ACS Omega 2019, 4, 5012-5018.
    https://doi.org/10.1021/acsomega.8b03551
    
    
11. Spálovská, D.; Maříková, T.; Kohout, M.; Králík, F.; Kuchař, M.; Setnička, V.: Methylone and pentylone: Structural analysis of new psychoactive substances. Forensic Toxicol. 2019, 37, 366-377.
    https://doi.org/10.1007/s11419-019-00468-z
    
    
12. Poryvai, A.; Bubnov, A.; Pociecha, D.; Svoboda, J.; Kohout, M.: The effect of the length of terminal n-alkyl carboxylate chain of self-assembling and photosensitive properties of chiral lactic acid derivatives. J. Mol. Liq. 2019, 275, 829-838.
    https://doi.org/10.1016/j.molliq.2018.11.058
    
    
13. Geibel, C.; Dittrich, K.; Woiwode, U.; Kohout, M.; Zhang, T.; Lindner, W.; Lämmerhofer, M.: Evaluation of superficially porous particle based zwitterionic chiral ion exchangers against fully porous particle benchmarks for enantioselective ultra-high performance liquid chromatography. J. Chromatogr. A 2019, 1603, 130-140.
    https://doi.org/10.1016/j.chroma.2019.06.026
    
    
14. Poryvai, A.; Vojtylová-Jurkovičová, T.; Šmahel, M.; Kolderová, N.; Tomášková, P.; Sýkora, D.; Kohout, M.: Determination of optical purity of lactic acid-based chiral liquid crystals and corresponding building blocks by chiral high-performance liquid chromatography and supercritical fluid chromatography. Molecules 2019, 24, 1099.
    10.3390/molecules24061099
    
    
15. Tlustý, M.; Eigner, V.; Babor, M.; Kohout, M.; Lhoták, P.: Synthesis of upper rim-double-bridged calix[4]arenes bearing seven membered rings and related compounds. RSC Adv. 2019, 9, 22017-22030.
    https://doi.org/10.1039/C9RA05075B
    
    
16. Horčic, M.; Svoboda, J.; Novotná, V.; Pociecha, D.: W-shaped mesogens and variations of their molecular structure. Liq. Cryst. 2019, 46, 816-824.
    https://doi.org/10.1080/02678292.2019.1573328
    
    
17. Cigl, M.; Jurok, R.; Hampl, F.; Svoboda, J.; Podoliak, N.; Novotná, V.: Lateral substituted phenyl biphenylcarboxylates – non-chiral analogues of ferroelectric liquid crystals. Liq. Cryst. 2019.
    https://doi.org/10.1080/02678292.2019.1679903
    
    
18. Kohout, M.; Hovorka, Š.; Herciková, J.; Wilk, M.; Sysel, P.; Izák, P.; Bartůněk, V.; von Baeckmann, C.; Pícha, J.; Frühauf, P.: Evaluation of silica from different vendors as the solid support of anion-exchange chiral stationary phases by means of preferential sorption and liquid chromatography. J. Sep. Sci. 2019, 42, 3653-3661.
    https://doi.org/10.1002/jssc.201900731

Publikace 2018

1. Jurásek, B.; Králík, F.; Rimpelová S.; Čejka, J.; Setnička, V.; Ruml, T.; Kuchař, M.; Kohout, M.:Synthesis, Absolute Configuration and in vitroCytotoxicity of Deschloroketamine Enantiomers: Rediscovered and Abused Dissociative Anaesthetic
   J. Chem. 2018, 42, 19360-19368 DOI: 10.1039/c8nj03107j
   
   
2. Landovsky, T.; Dvorakova, H.; Eigner, V.; Babor, M.; Krupicka, M.; Kohout, M.; Lhotak, P.:Chemoselective Oxidation of Phenoxathiin-based Thiacalix[4]arene and the Stereoselective Alkylation of Products
   New J. Chem.2018, 42, 20074-20086 DOI: 1039/C8NJ04690E
   
   
3. Schmitt, K.; Woiwode, U.; Kohout, M.; Zhang, T.; Lindner, W.; Lämmerhofer, M.:
   Comparison of small size fully porous particles and superficially porous particles of chiral anion-exchange type stationary phases in ultra-high performance liquid chromatography: effect of particle and pore size on chromatographic efficiency and kinetic performance
   Chromatogr. A2018, 1569, 149-159 DOI:10.1016/j.chroma.2018.07.056
   
   
4.  Spálovská, D.; Kralik, F.; Kohout, M.; Jurasek, B.; Habartová, L.; Kuchar, M.; Setnicka, V.: Structure determination of butylone as a new psychoactive substance using chiroptical and vibrational spectroscopies 
   Chirality2018, 30, 548-559 DOI:1002/chir.22825
   
   
5. Wolrab, D.; Kohout, M.: Multimodální stacionární fáze pro kapalinovou chromatografii, způsob jejich přípravy a jejich použití. Národní patent č. 307339, číslo přihlášky 2017-193, datum udělení 2.5.2018, datum zveřejnění 13.6.2018.
   
   
6. Kohout, M.; Wernisch, S.; Tuma, J.; Hettegger, H.; Picha, J.; Lindner W.: Effect of different immobilization strategies on chiral recognition properties of Cinchona-based anion exchangers 
   Sep. Sci.2018, 41, 1355-1364 DOI:10.1002/jssc.201701213
   
   
7. Bajtai, A.; Fekete, B.; Palkó, M.; Fülöp, F.; Lindner, W.; Kohout, M.; Ilisz, I.; Péter, A.:  Comparative study on the liquid chromatographic enantioseparation of cyclic β-amino acids and the related cyclic β-aminohydroxamic acids on Cinchona alkaloid-based zwitterionic chiral stationary phases 
   Sep. Sci.2018, 41, 1216-1223 DOI:10.1002/jssc.201701190
   
   
8. Sardella, R.; Macchiarulo, A.; Urbinati, F.; Ianni, F.; Carotti, A.; Kohout, M.; Lindner, W.; Péter, A.; Ilisz, I.: Exploring the enantiorecognition mechanism of Cinchona alkaloid-based zwitterionic chiral stationary phases and the basic trans-paroxetine enantiomers 
   Sep. Sci.2018, 41, 1199-1207 DOI:10.1002/jssc.201701068
   
   
9. Tuma, J.; Kohout, M.: Silica gel-immobilized multidisciplinary materials applicable in stereoselective organocatalysis and HPLC separation 
   RSC Adv.2018, 8, 1174-1181 DOI:1039/c7ra12658a
   
   
10. Kozmik, V.; Rodinová, E.; Prausová, T.; Svoboda, J.; Novotná, V.; Pociecha, D.: Mesogens with central naphthalene core substituted at various positions 
    Cryst. 2018, 45, 744-756 DOI: 10.1080/02678292.2017.1380238
    
    
11. Bajzíková, K.; Vesely, J.; Kozmik, V.; Svoboda, J.; Novotná, V.; Pociecha, D.: Thiophene central core for the design of bent-shaped liquid crystals 
    Mol. Liq. 2018, 267, 496-503 DOI:10.1016/j.molliq.2018.02.009
    
    
12. Horcic, M.; Svoboda, J.; Novotná, V.; Pociecha, D.; Gorecka, E.: Bent-core dimers with top-to-bottom linkage between central units 
    RSC Adv. 2018, 8, 22974-22985 DOI: 1039/c8ra04108c
    
    
13. Marz, M.; Kohout, M.; Nevesely, T.; Chudoba, J.; Prukala, D.; Nizinski, S.; Sikorski, M.; Burdzinski, G.; Cibulka, R.:Azodicarboxylate-free esterification with triphenylphosphine mediated by flavin and visible light: method development and stereoselectivity control
    Biomol. Chem.2018, 16, 6809-6817 DOI:10.1039/C8OB01822G

Publikace 2017

4. Maixner, J.; Jurásek, B.; Kohout, M.; Kuchar, M.; Kacer, P.: X-ray powder diffraction data for (S)-Deschloroketamine hydrochloride, C₁₃H₁₈ Powder Diffr.2017, 32, 193-195. DOI:10.1017/S0885715617000586
   
   
5. Bajzíková, K.; Svoboda, J.; Novotná, V.; Pociecha, D.; Gorecka E.: Bent-core mesogens with an aromatic unit at the terminal position. New J. Chem.2017, 41, 4672-4679 DOI: 1039/C6NJ03908A
   
   
6. Žurek, J.; Svobodová, E.; Šturala, J.; Dvořáková, H.;Svoboda, J.; Cibulka, R.: Chiral ethylene-bridged flavinium salts: The stereoselectivity of flavin-10a-hydroperoxide formation and the effect of substitution on the photochemical properties. Tetrahedron Asymmetry 2017, 28, 1780-1791. DOI:1016/j.tetasy.2017.10.029
   
   
7. Dobrovolny, K.; Ulbrich, P.; Svecova, M.; Rimpelova, S.; Malincik, J.; Kohout, M.; Svoboda, J.; Bartunek, V.: Copper nanoparticles in glycerol-​polyvinyl alcohol matrix: In situ preparation, stabilization and antimicrobial aktivity. Alloy. Compd.2017, 697, 147-155 DOI:10.1016/j.jallcom.2016.12.144
   
   
8. Kolderova, N.; Nevesely, T.; Sturala, J.; Kuchar, M.; Holakovsky, R.; Kohout, M.:
   Enantioseparation of chiral sulfoxides on amylose-​based columns: comparison of normal phase liquid chromatography and supercritical fluid chromatography Chromatographia 2017, 80, 547-557 DOI: 10.1007/s10337-016-3234-6
   
   
9. Kohout, M.; Alaasar, M.; Poryvai, A.; Novotna, V.; Poppe, S.; Tschierske, C.; Svoboda, J.: Photosensitive bent-​core liquid crystals based on methyl substituted 3-​hydroxybenzoic acid
   RSC Adv.2017, 7, 35805-35813 DOI:10.1039/C7RA05632J
   
   
10. Wolrab, D.; Fruehauf, P.; Gerner, C.; Kohout, M.;Lindner, W.: Consequences of transition from liquid chromatography to supercritical fluid chromatography on the overal performance of a chiral zwitterionic ion-​exchanger. J. Chromatogr. A 2017, 1517, 165-175 DOI:10.1016/j.chroma.2017.08.022
    
    
11. Pallova, L.;Kozmik, V.; Kohout, M.; Svoboda, J.; Novotna, V.; Pociecha, D.: Bent-​core liquid crystals with a 2-​substituted 3-​hydroxybenzoic acid central core. Cryst. 2017, 44, 1306-1315 DOI: 10.1080/02678292.2016.1276981
    
    
12. Tlusty, M.; Slavik, P.; Kohout, M.; Eigner, V.; Lhotak, P.: Inherently Chiral Upper-Rim-Bridged Calix[4]arenes Possessing a Seven Membered Ring
    Org. Lett. 2017, 19, 2933-2936 DOI:10.1021/acs.orglett.7b01170
    
    
13. Miksatko, J.; Eigner, V.; Kohout, M.; Lhotak, P.: Regio-/stereoselective Formation of Monosulfoxides from Thiacalix[4]arenes in All Possible Conformations
    Tetrahedron Letters 2017, 58, 1687–1691 DOI:10.1016/j.tetlet.2017.03.043
    
    
14. Horčic, M.; Kohout, M.; Svoboda, J.; Novotna, V.; Pociecha, D.; Gorecka, E.: Core-to-core Dimers Forming Switchable Mesophase
    Chem.  Commun. 2017, 53, 2721-2724 DOI:10.1039/C6CC09983A
    
    
15. März, M.; Chudoba, J.; Kohout, M.; Cibulka, R.: Photocatalytic Esterification under Mitsunobu Reaction Conditions Mediated by Flavin and Visible Light
    Org. Biomol. Chem. 2017, 15, 1970-1975 DOI:10.1039/C6OB02770A

Publikace 2016

1. Bajzikova, K.; Kohout, M.; Tarabek, J.; Svoboda, J.; Novotna, V.; Vejpravova, J.; Pociecha, D.; Gorecka, E.: All-organic liquid crystalline radicals with a spin unit in the outer position of a bent-core systém. J. Mater. Chem. C2016, 4, 11540-11547.  DOI:10.1039/C6TC04346A
   
   
2. Tůma, J.; Kohout, M.; Svoboda, J.; Novotná, V.; Pociecha, D.: Bent-core liquid crystals based on 6-substituted 3-hydroxybenzoic acid: the role of substitution and linkage group orientation on mesomorphic properties. Liq. Cryst.2016, 43, 1889-1900.  DOI:10.1080/02678292.2016.1230789
   
   
3. Kohout, M.; Vandenbussche, J.; Roller, A.; Tůma, J.; Boqaerts, J.; Bultinck, P.; Herrebout, W.; Lindner, W.: Absolute configuration of the antimalarial erythro-mefloquine - vibrational dichroism and X-ray diffraction studies of mefloquine and its thiourea derivative. RSC Advances2016, 6, 81461-81465. DOI:1039/C6RA19367F 
   
   
4. Kohout, M.; Bubnov, A.; Šťurala, J.; Novotná, V.; Svoboda, J.: Effect on alkyl chain length in the terminal ester group on mesomorphic properties of new chiral lactic acid derivatives. Cryst.2016, 43, 1472-1485. DOI:10.1080/02678292.2016.1185170
   
   
5. Grecsó, N.; Kohout, M.; Carotti, A.; Sardella, R.; Natalini, B.; Fülöp, F.; Lindner, W.; Péter, A.; Ilisz, I.: Mechanistic considerations of enantiorecognition on novel Cinchona alkaloid-based zwitterionic chiral stationary phases from the aspect of the separation of trans-paroxetine enantiomers as model compounds. Pharm. Biomed. Anal.2016, 124, 164-173. DOI:10.1016/j.jpba.2016.02.043
   
   
6. Wolrab, D.; Frühauf, P.; Moulisova, A.; Kuchar, M.; Gerner, C.; Lindner, W.; Kohout, M.: Chiral separation of new designer drugs (Cathinones) on chiral ion-exchange type stationary phases. Pharm. Biomed. Anal.2016, 120, 306-315. DOI:10.1016/j.jpba.2015.12.023
   
   
7. Tůma, J.; Kohout, M.; Svoboda, J.; Novotná, V.; Pociecha, D.: Bent-shaped liquid crystals based on 4-substituted 3-hydroxybenzoic acid central core - Part II.  Cryst. 2016, 43, 547-563 DOI: 10.1080/02678292.2015.1125535
   
   
8. Slavik, P.; Kohout, M.; Böhm, S.; Eigner, V.; Lhotak, P.: Synthesis of Inherently Chiral Calixarenes via Direct Mercuration of the Partial Cone Conformation. Chem. Comm.  2016, 52, 2366-2360 DOI:10.1039/C5CC09388K

Publikace 2015

5. Trišović, N.; Antanasijević, J.; Tóth-Katona, T.; Kohout, M.; Salamonczyk, M.; Sprunt, S.; Jákli, A.; Fodor-Csorba, K.: Azo-containing asymmetric bent-core liquid crystals with modulated smectic phase RSC Adv. 2015, 5, 64886-64891. DOI: 10.1039/c5ra09764a
   
   
6. Kohout, M.; Bielec, B.; Steindl, P.; Trettenhahn, G.; Lindner, W.: Mechanistic aspects of the direct C-acylation of cyclic 1,3-diones with various unactivated carboxylic acids Tetrahedron 2015, 71, 2698-2707. DOI: tet.2015.03.037
   
   
7. von Koschitzky, I.; Gerhardt, H.; Lämmerhofer, M.; Kohout, M.; Gehringer, M.; Laufer, S.; Pink, M.; Schmitz-Spanke, S.; Strube, C.; Kaiser, A.: New insights into novel inhibitors against deoxyhypusine hydrolase from plasmodium falciparum: compounds with an iron chelating potential Amino Acids 2015, 47, 1155-1166. DOI: 1007/s00726-015-1943-z
   
   
8. Kohout, M.; Kozmík, V.; Slabochová, M.; Tůma, J.; Svoboda, J.; Novotná, V.; Pociecha, D.: Bent-shaped liquid crystals based on 4-substituted 3-hydroxybenzoic acid central core Cryst. 2015, 42, 87-103. DOI: 10.1080/02678292.2014.965232
   
   
9. Kozmík, V.; Poznik, M.; Svoboda, J.; Frere, P.:
   Dithieno[3,2-b:2',3'-d]furan as a new building block for fused conjugated systems
   Tetrahedron Lett.2015, 56, 6251-6253. DOI:10.1016/j.tetlet.2015.09.107