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Papers (since the establishment of the group) 

  1. R. Chavan, M. Besch, J. Lefèbre, C. Rademacher, P. Ménová*: Aryl fucosides: synthesis and evaluation of their binding affinity towards the DC-SIGN receptor. Org. Bioorg. Chem. 2025, Advance Article. https://doi.org/10.1039/D5OB00472A

  2. R. Chavan, J. Lefebre, K. Jochová, H. Dvořáková, C. Rademacher, P. Ménová*: Fucosyl glycosides for DC-SIGN targeting: Fucosylation strategies, synthesis and binding studies of model compounds. Bioorg. Med. Chem. 2025, 123, 118164. https://doi.org/10.1016/j.bmc.2025.118164

  3. J. Ledvinka, F. Rota Sperti, G. Paragi, M. Pirrotta, N. Chéron, I. E. Valverde, P. Menova*, D. Monchaud: Fluorescence Detection of DNA/RNA G-Quadruplexes (G4s) by Twice-as-Smart Ligands. ChemMedChem 2025, e202400829. https://doi.org/10.1002/cmdc.202400829

  4. F. Ramírez-Cortés, P. Ménová*: Hepatocyte targeting via the asialoglycoprotein receptor. RSC Med. Chem. 2025, 16, 525–544. https://doi.org/10.1039/D4MD00652F

  5. S. Leusmann, P. Ménová, E. Shanin, A. Titz, C. Rademacher: Glycomimetics for the inhibition and modulation of lectins. Chem. Soc. Rev. 2023, 52, 3663–3740. https://doi.org/10.1039/D2CS00954D.

  6. H. Zhang, O. Daněk, D. Makarov, S. Rádl, D. Kim, J. Ledvinka, K. Vychodilová, J. Hlaváč, J. Lefèbre, M. Denis, C. Rademacher, P. Ménová*: Drug-like Inhibitors of DC-SIGN Based on a Quinolone Scaffold, ACS Med. Chem. Lett. 2022, 13, 935–942. https://doi.org/10.1021/acsmedchemlett.2c00067.

  7. Ménová: ASGPR a DC-SIGN: C-lektinové receptory se slibným potenciálem v medicinální chemii. Chem. Listy 2021, 115, 126–133.

 Previous papers by Petra Ménová, written before the group was etablished 

  1. A. Golczak, M. Insińska-Rak, A. Davoudpour, D. H. Saeed, P. Ménová, V. Mojr, R. Cibulka, I. Khmelinskii, L. Mrówczyńska, M. Sikorski: Photophysical properties of alloxazine derivatives with extended aromaticity – Potential redox-sensitive fluorescent probe, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2022, 272, 120985. https://doi.org/10.1016/j.saa.2022.120985.

  2. P. Kaplonek, L. Yao, K. Reppe, F. Voß, T. Kohler, F. Ebner, A. Schäfer, U. Blohm, P. Priegue, M. Bräutigam, C. L. Pereira, S. G. Parameswarappa, M. Emmadi, P. Ménová, M. Witzenrath, S. Hammerschmidt, S. Hartmann, L. E. Sander, P. H. Seeberger: A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae, Vaccine 2022, 40 (7), 1038–1046. https://doi.org/10.1016/j.vaccine.2021.12.068.

  3. P. Ménová, M. Sella, K. Sellrie, C. Pereira, P. H. Seeberger: Identification of the minimal glycotope of Streptococcus pneumoniae 7F capsular polysaccharide using synthetic oligosaccharides, Chem. Eur. J. 2018, 24, 4181–4187. https://doi.org/10.1002/chem.201705379

  4. S. G. Parameswarappa, K. Reppe, A. Geissner, P. Ménová, S. Govindan, A. D. J. Calow, A. Wahlbrink, M. W. Weishaupt, B. P. Monnanda, R. L. Bell, L.-A. Pirofski, N. Suttorp, L. E. Sander, M. Witzenrath, C. L. Pereira, C. Anish, P. H. Seeberger: A semi-synthetic oligosaccharide conjugate vaccine candidate confers protection against Streptococcus pneumoniae serotype 3 infection, Cell Chem. Biol. 2016, 23, 1407–1416. https://doi.org/10.1016/j.chembiol.2016.09.016

  5. D. Hocková, Š. Rosenbergová, P. Ménová, O. Páv, R. Pohl, P. Novák, I. Rosenberg: N-Branched acyclic nucleoside phosphonates as monomers for the synthesis of modified oligonucleotides, Org. Biomol. Chem. 2015, 13, 4449–4458. https://doi.org/10.1039/C4OB02265C

  6. P. Ménová, D. Dziuba, P. Güixens-Gallardo, P. Jurkiewicz, M. Hof, M. Hocek: Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction, Bioconjugate Chem. 2015, 26, 361–366. https://doi.org/10.1021/acs.bioconjchem.5b00006

  7. P. Ménová, H. Dvořáková, V. Eigner, J. Ludvík, R. Cibulka: Electron-deficient alloxazinium salts: efficient organocatalysts of mild and chemoselective sulfoxidations with hydrogen peroxide, Adv. Synth. Catal. 2013, 355, 3451–3462. https://doi.org/10.1002/adsc.201300617

  8. P. Ménová, V. Raindlová, M. Hocek: Scope and Limitations of the Nicking Enzyme Amplification Reaction for the Synthesis of Base-Modified Oligonucleotides and Primers for PCR, Bioconjugate Chem. 2013, 24, 1081–1093. https://doi.org/10.1021/bc400149q

  9. P. Perlíková, L. Eberlin, P. Ménová, V. Raindlová, L. Slavětínská, E. Tloušťová, G. Bahador, Y.-J. Lee, M. Hocek: Synthesis and Cytostatic and Antiviral Activities of 2’-Deoxy-2’,2’-difluororibo- and 2’-Deoxy-2’-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines, ChemMedChem 2013, 8, 832–846. https://doi.org/10.1002/cmdc.201300047

  10. P. Ménová, H. Cahová, M. Plucnara, L. Havran, M. Fojta, M. Hocek: Polymerase synthesis of oligonucleotides containing a single chemically modified nucleobase for site-specific redox labelling,  2Chem. Commun. 2013, 49, 4652–4654. https://doi.org/10.1039/C3CC41438H

  11. J. Riedl, P. Ménová, R. Pohl, P. Orság, M. Fojta, M. Hocek: GFP-like fluorophores as DNA labels for studying     DNA–protein interactions, J. Org. Chem. 2012, 77, 8287–8293. https://doi.org/10.1021/jo301684b

  12. P. Ménová, R. Cibulka: Insight into the catalytic activity of alloxazinium and isoalloxazinium salts in the oxidations of sulfides and amines with hydrogen peroxide, J. Mol. Catal. A–Chem. 2012, 363-364, 362–370. https://doi.org/10.1016/j.molcata.2012.07.012
  13. P. Ménová, M. Hocek: Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction, Chem. Commun. 2012, 48, 6921–6923. https://doi.org/10.1039/C2CC32930A

  14. M. Pluncara, H. Pivoňková, L. Havran, M. Hocek, P. Ménová, H. Cahová, J. Balintová, M. Fojta: Site-specific labeling of nucleotides in DNA strand for possible usage in electrochemical DNA-sensors, FEBS J. 2012, 279, 571–572.

  15. P. Ménová, V. Eigner, J. Čejka, H. Dvořáková, M. Šanda, R. Cibulka: Synthesis and structural studies of flavin and alloxazine adducts with O-nucleophiles, J. Mol. Struct. 2011, 1004, 178–187. https://doi.org/10.1016/j.molstruc.2011.08.002

  16. P. Ménová, F. Kafka, H. Dvořáková, S. Gunnoo, M. Šanda, R. Cibulka: Pyrazinium salts as efficient organocatalysts of mild oxidations with hydrogen peroxide, Adv. Synth. Catal. 2011, 353, 865–870. https://doi.org/10.1002/adsc.201000906

  17. P. Ménová, V. Eigner, R. Cibulka, J. Čejka, H. Dvořáková: 5-Ethyl-4a-methoxy-1,3-dimethyl-4a,5-dihydrobenzo[g]pteridine-2,4(1H,3H)dione, Acta Cryst. E 2009, E65, o1536–o1537. https://doi.org/10.1107/S1600536809020856

  18. R. Cibulka, L. Baxová, H. Dvořáková, F. Hampl, P. Ménová, V. Mojr, B. Plancq, S. Sayin: Catalytic effect of alloxazinium and isoalloxazinium salts on oxidation of sulfides with hydrogen peroxide in micellar media, Collect. Czech. Chem. Commun. 2009, 74, 973–993. https://doi.org/10.1135/cccc2009030 

Patents 

  1. P. Seeberger, C. L. Pereira, S. Parameswarappa, A. Calow, P. Ménová, S. Govindan: Improved preparation of vaccines against Streptococcus pneumoniae type 3, EP3231810A1, WO2017178664-A1, EP3292131-A1.

  2. P. Seeberger, C. L. Pereira, M. Emmadi, S. Parameswarappa, A. Calow, P. Ménová, M. Lisboa, Ch. Martin, B. Schumann, F. Xu, N. Khan, P. Kaplonek, L. Lykke: Pneumococcal oligosaccharide-protein conjugate composition, WO2017220753, EP16179133.0.

Books and book chapters 

  1. P. Ménová, F. Hampl: Základy farmakochemie. VŠCHT Praha 2022. ISBN 978-80-7592-119-2.

  2. P. Holzhauser, R. Matuška, P. Ménová: Použití chemických látek ve výuce a při volnočasových aktivitách žáků. Czech Chem. Soc. Symp. Ser. 2019, 17, 87–122. ISBN 2336-7202.

  3. P. Ménová, H. Cahová, M. Vrábel, M. Hocek: Synthesis of Base-Modified dNTPs Through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA. In: Shank N. (eds) Non-Natural Nucleic Acids. Methods in Molecular Biology, 2019, 1973, 39–57. Humana Press, New York, NY. Print ISBN 978-1-4939-9215-7, online ISBN 978-1-4939-9216-4.

  4. P. Ménová: The IChO Theoretical Exam. In: F. M. Fung, I–J. Chang (eds): 10 Things You Must Know about International Chemistry Olympiad: A Guide to the IChO Competition, 2019, 29–35. Chang-Xin Cultural & Creative Marketing. ISBN 978-986-97513-5-3. 


Bachelor theses

  1. Novotný Vít: Synthesis of a library of chromones and evaluation of their affinity for DC-SIGN receptor       (2025)
     
  2. Kučerová Kamila: Synthesis of M2-selective muscarinic receptor agonists and evaluation of their       biological aktivity (2025)

  3. Schimmer Jakub: Diaryl mannosides and their binding affinity for DC-SIGN receptor (2023)

  4. Brokeš Martin: Quinoxalinone-based DC-SIGN inhibitors (2023)

  5. Daněk Ondřej: Synthesis of quinolone-based DC-SIGN inhibitors (2022)

  6. Wohlgemuth Jan: Synthesis of 2-phenylsulfonyacrylates as potential inhibitors of DC-SIGN receptor (2022)

  7. Jochová Kateřina: Modified nanoparticles for DC-SIGN targeting (2021)

  8. Ledvinka Jiří: Synthesis of mannose-based DC-SIGN antagonists (2020)

  9. Musil Vojtěch: Synthesis of quinoxalinone-based inhibitors of DC-SIGN receptor (2020)

  10. Wohlrábová Lucie: Chelating lipids for optical quantum nanosensors (2019)

  11. Makarov Dmytro: Syntéza substituovaných chinolonů jako potenciálních inhibitorů DC-SIGN receptoru (2018) 

 

Master theses

  1. Karepova Darja: Synthesis of DC-SIGN ligands based on arylsulfonyl acrylate (2025)

  2. Stara František: Synthesis and evaluation of hydroxyquinolones for the treatment of skin diseases (2025)

  3. Wohlgemuth Jan: Synthesis of ligands for DC-SIGN receptor (2024)

  4. Daněk Ondřej: Synthesis of novel M2-selective muscarinic receptor agonists (2024)

  5. Kramný Vojtěch: Small-molecule ligands for DC-SIGN receptor (2023)

  6. Jochová Kateřina: Ligands and nanoparticles for DC-SIGN targeting (2023)

  7. Ledvinka Jiří: G-quadruplex (G4) smart probes to investigate G4s cellular functions (2022)

  8. Makarov Dmytro: Synthesis of quinolone-based inhibitors of DC-SIGN receptor (2020)

  9. Mornat Pauline: Synthesis of mannose-based DC-SIGN inhibitors bearing fluorinated arene moiety (2019) 


Doctoral theses 

  1. Chavan Rohit

  2. Ramírez-Cortés Fabricio 
Updated: 31.7.2025 14:55, Author: Jan Budka


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